Linking autoimmunity to the origin of the adaptive immune system
نویسندگان
چکیده
منابع مشابه
Linking autoimmunity to the origin of the adaptive immune system
In jawed vertebrates, the adaptive immune system (AIS) cooperates with the innate immune system (IIS) to protect hosts from infections. Although targeting non-self-components, the AIS also generates self-reactive antibodies which, when inadequately counter-selected, can give rise to autoimmune diseases (ADs). ADs are on the rise in western countries. Why haven't ADs been eliminated during the e...
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ژورنال
عنوان ژورنال: Evolution, Medicine, and Public Health
سال: 2018
ISSN: 2050-6201
DOI: 10.1093/emph/eoy001